First episode, acute psychosis, relapse prevention

Introduction to this topic

Professor Peter Jones
Professor of Psychiatry, University of Cambridge

Updated: Thursday, 7th July 2016
Last Checked: Friday, 3rd February 2017 Current

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This topic describes an evidence-based, patient-centred approach to the use of antipsychotic medication in a comprehensive treatment plan, with particular emphasis on the first psychotic episode and prevention of relapse following symptom remission. The importance of early treatment experiences is stressed regarding setting the scene for recovery, and the need for active management to minimise adverse effects. Other issues addressed include how long to treat after the first episode, the evidence for the importance of maintenance antipsychotic drug treatment in relapse prevention, and the lack of protection from low-dose or intermittent treatment. Evidence from the CATIE, CUtLASS and subsequent trials emphasizes the need for careful prescribing and management for people with chronic schizophrenia, rather than suggesting any clear advantage of second generation over first generation antipsychotics in terms of effectiveness, safety or costs.

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Sections in this Topic

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First Episode, Acute Treatment, Relapse Prevention - Introduction

Duration: 04m 30s
No. of slides: 6 - View Slide List

Play the video for Section

First Episode

Duration: 14m 44s
No. of slides: 20 - View Slide List

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First episode and relapse prevention; Most people get better, but some may relapse

Duration: 15m 07s
No. of slides: 16 - View Slide List

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Summary in first episode psychosis

Duration: 19m 22s
No. of slides: 18 - View Slide List