Maintenance treatment in bipolar disorder

Introduction to this topic

Presenter:
Professor Peter Haddad
Consultant Psychiatrist, Greater Manchester Mental Health NHS Foundation Trust and Honorary Clinical Professor of Psychiatry, University of Manchester

Updated: Monday, 21st October 2019
Last Checked: Monday, 21st October 2019 Current

Supporting Files

Supporting files for this topic are available if you have a current CPD subscription.

The long-term treatment of bipolar disorder aims to prevent recurrence of both manic and depressive episodes and is essential given the highly recurrent nature of the disorder. Until recently lithium and carbamazepine were the only drugs licensed in the UK for long-term treatment of bipolar disorder but recent years have seen the approval of lamotrigine and several second generation antipsychotics as maintenance agents. In addition valproate, although unlicensed as a maintenance agent in the UK, has supportive date. This presentation reviews the evidence for the efficacy of these agents and shows that most are more effective in preventing recurrence at either the depressive or manic pole. Recent date relating to long-term combination treatment, including the BALANCE trial, is discussed.

Back to Bipolar Disorder

NB you need to be logged in and your subscription must be up to date in order to view the presentations below

Sections in this Topic

Play the video for Section

Maintenance Pharmacological Treatment of Bipolar Disorder

Duration: 15m 52s
No. of slides: 15 - View Slide List


Play the video for Section

Lithium and Anticonvulsants in Maintenance Treatment

Duration: 05m 54s
No. of slides: 7 - View Slide List


Play the video for Section

Antipsychotics in Monotherapy in Maintenance Treatment

Duration: 09m 24s
No. of slides: 8 - View Slide List


Play the video for Section

Drug Combinations in Long Term Treatment

Duration: 04m 59s
No. of slides: 8 - View Slide List


Play the video for Section

Summary and Conclusions

Duration: 04m 41s
No. of slides: 5 - View Slide List